Cardiac phenotype of mitochondrial creatine kinase knockout mice is modified on a pure C57BL/6 genetic background.

UNLABELLED: Discrepant results for the phenotype of mitochondrial creatine kinase knockout mice (Mt-CK(-/-)) could be due to mixed genetic background and use of non-littermate controls. We therefore backcrossed with C57BL/6J for >8 generations, followed by extensive in vivo cardiac phenotypin...

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Bibliographic Details
Main Authors: Lygate, C, Hunyor, I, Medway, D, de Bono, J, Dawson, D, Wallis, J, Sebag-Montefiore, L, Neubauer, S
Format: Journal article
Language:English
Published: 2009