DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation
Enhancer elements are a key regulatory feature of many important genes. Several general features including the presence of specific histone modifications are used to demarcate potentially active enhancers. Here we reveal that putative enhancers marked with H3 lysine 79 (H3K79) di or trimethylation (...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Journal article |
| Published: |
Springer Nature
2019
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