A 'Build and Retrieve' methodology to simultaneously solve cryo-EM structures of membrane proteins

Single-particle cryo-electron microscopy (cryo-EM) has become a powerful technique in the field of structural biology. However, the inability to reliably produce pure, homogeneous membrane protein samples hampers the progress of their structural determination. Here, we develop a bottom-up iterative...

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Bibliographic Details
Main Authors: Su, C-C, Lyu, M, Morgan, CE, Bolla, JR, Robinson, CV, Yu, EW
Format: Journal article
Language:English
Published: Springer Nature 2021