Hepatitis B virus genome recycling and de novo secondary infection events maintain stable cccDNA levels

<strong>Background &amp; Aims:</strong> Several steps in the HBV life cycle remain obscure because of a lack of robust in vitro infection models. These steps include particle entry, formation and maintenance of covalently closed circular (ccc) DNA, kinetics of gene expression and vir...

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Detalhes bibliográficos
Principais autores: Ko, C, Chakraborty, A, Chou, W, Hasreiter, J, Wettengel, J, Stadler, D, Bester, R, Asen, T, Zhang, K, Wisskirchen, K, McKeating, J, Ryu, W, Protzer, U
Formato: Journal article
Publicado em: Elsevier 2018