Relationship of NAD(P)H oxidase activity in human blood vessels to endothelial dysfunction and clinical risk factors

Vascular superoxide production is increased in animal models of atherosclerosis, diabetes and hypertension, and reduces nitric oxide (NO) bioactivity. However, the functional importance of superoxide production in human atherosclerosis is poorly characterised. We aimed to determine the relationships...

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Bibliographic Details
Main Authors: Guzik, T, West, N, Black, E, McDonald, D, Ratnatunga, C, Pillai, R, Channon, K
Format: Journal article
Language:English
Published: 2000