Selective metal-site-guided arylation of proteins
We describe a palladium-mediated S-arylation method that exploits natural metal-binding motifs to ensure high site-selectivity for a proximal reactive residue. This allows the chemical identification not only of proteins that bind metals but the environment of the metal binding site itself through p...
| Main Authors: | , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
American Chemical Society
2016
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