The calcium-sensing receptor in physiology and in calcitropic and noncalcitropic diseases

The Ca2+-sensing receptor (CaSR) is a dimeric family C G protein-coupled receptor that is expressed in calcitropic tissues such as the parathyroid glands and the kidneys and signals via G proteins and β-arrestin. The CaSR has a pivotal role in bone and mineral metabolism, as it regulates parathyroid...

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Bibliographic Details
Main Authors: Hannan, F, Kallay, E, Chang, W, Brandi, M, Thakker, R
Format: Journal article
Published: Springer Nature 2018