Efficient second strand cleavage during Holliday junction resolution by RuvC requires both increased junction flexibility and an exposed 5' phosphate

<p>Background: Holliday junction (HJ) resolution is a critical step during homologous recombination. In <em>Escherichia coli</em> this job is performed by a member of the RNase H/Integrase superfamily called RuvC, whereas in <em>Schizosaccharomyces pombe</em> it has be...

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Bibliographic Details
Main Authors: Osman, F, Gaskell, L, Whitby, M
Format: Journal article
Language:English
Published: Public Library of Science 2009
Subjects: