Efficient second strand cleavage during Holliday junction resolution by RuvC requires both increased junction flexibility and an exposed 5' phosphate
<p>Background: Holliday junction (HJ) resolution is a critical step during homologous recombination. In <em>Escherichia coli</em> this job is performed by a member of the RNase H/Integrase superfamily called RuvC, whereas in <em>Schizosaccharomyces pombe</em> it has be...
Main Authors: | , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2009
|
Subjects: |