Gene amplification of the multidrug resistance 1 gene of Plasmodium vivax isolates from Thailand, Laos, and Myanmar.

Plasmodium vivax mdr1 gene amplification, quantified by real-time PCR, was significantly more common on the western Thailand border (6 of 66 samples), where mefloquine pressure has been intense, than elsewhere in southeast Asia (3 of 149; P = 0.02). Five coding mutations in pvmdr1, independent of ge...

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主要な著者: Imwong, M, Pukrittayakamee, S, Pongtavornpinyo, W, Nakeesathit, S, Nair, S, Newton, P, Nosten, F, Anderson, T, Dondorp, A, Day, N, White, N
フォーマット: Journal article
言語:English
出版事項: 2008