Gene amplification of the multidrug resistance 1 gene of Plasmodium vivax isolates from Thailand, Laos, and Myanmar.
Plasmodium vivax mdr1 gene amplification, quantified by real-time PCR, was significantly more common on the western Thailand border (6 of 66 samples), where mefloquine pressure has been intense, than elsewhere in southeast Asia (3 of 149; P = 0.02). Five coding mutations in pvmdr1, independent of ge...
| Автори: | , , , , , , , , , , |
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| Формат: | Journal article |
| Мова: | English |
| Опубліковано: |
2008
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| _version_ | 1826299288109449216 |
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| author | Imwong, M Pukrittayakamee, S Pongtavornpinyo, W Nakeesathit, S Nair, S Newton, P Nosten, F Anderson, T Dondorp, A Day, N White, N |
| author_facet | Imwong, M Pukrittayakamee, S Pongtavornpinyo, W Nakeesathit, S Nair, S Newton, P Nosten, F Anderson, T Dondorp, A Day, N White, N |
| author_sort | Imwong, M |
| collection | OXFORD |
| description | Plasmodium vivax mdr1 gene amplification, quantified by real-time PCR, was significantly more common on the western Thailand border (6 of 66 samples), where mefloquine pressure has been intense, than elsewhere in southeast Asia (3 of 149; P = 0.02). Five coding mutations in pvmdr1, independent of gene amplification, were also found. |
| first_indexed | 2024-03-07T04:59:38Z |
| format | Journal article |
| id | oxford-uuid:d7d6e71d-0b85-441c-83c2-1ebb56d52a03 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:59:38Z |
| publishDate | 2008 |
| record_format | dspace |
| spelling | oxford-uuid:d7d6e71d-0b85-441c-83c2-1ebb56d52a032022-03-27T08:43:55ZGene amplification of the multidrug resistance 1 gene of Plasmodium vivax isolates from Thailand, Laos, and Myanmar.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d7d6e71d-0b85-441c-83c2-1ebb56d52a03EnglishSymplectic Elements at Oxford2008Imwong, MPukrittayakamee, SPongtavornpinyo, WNakeesathit, SNair, SNewton, PNosten, FAnderson, TDondorp, ADay, NWhite, NPlasmodium vivax mdr1 gene amplification, quantified by real-time PCR, was significantly more common on the western Thailand border (6 of 66 samples), where mefloquine pressure has been intense, than elsewhere in southeast Asia (3 of 149; P = 0.02). Five coding mutations in pvmdr1, independent of gene amplification, were also found. |
| spellingShingle | Imwong, M Pukrittayakamee, S Pongtavornpinyo, W Nakeesathit, S Nair, S Newton, P Nosten, F Anderson, T Dondorp, A Day, N White, N Gene amplification of the multidrug resistance 1 gene of Plasmodium vivax isolates from Thailand, Laos, and Myanmar. |
| title | Gene amplification of the multidrug resistance 1 gene of Plasmodium vivax isolates from Thailand, Laos, and Myanmar. |
| title_full | Gene amplification of the multidrug resistance 1 gene of Plasmodium vivax isolates from Thailand, Laos, and Myanmar. |
| title_fullStr | Gene amplification of the multidrug resistance 1 gene of Plasmodium vivax isolates from Thailand, Laos, and Myanmar. |
| title_full_unstemmed | Gene amplification of the multidrug resistance 1 gene of Plasmodium vivax isolates from Thailand, Laos, and Myanmar. |
| title_short | Gene amplification of the multidrug resistance 1 gene of Plasmodium vivax isolates from Thailand, Laos, and Myanmar. |
| title_sort | gene amplification of the multidrug resistance 1 gene of plasmodium vivax isolates from thailand laos and myanmar |
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