Influence of irofulven, a transcription-coupled repair-specific antitumor agent, on RNA polymerase activity, stability and dynamics in living mammalian cells.

Influence of irofulven, a transcription-coupled repair-specific antitumor agent, on RNA polymerase activity, stability and dynamics in living mammalian cells.

Transcription-coupled repair (TCR) plays a key role in the repair of DNA lesions induced by bulky adducts and is initiated when the elongating RNA polymerase II (Pol II) stalls at DNA lesions. This is accompanied by alterations in Pol II activity and stability. We have previously shown that the mono...

Bibliografski detalji
Glavni autori:	Escargueil, A, Poindessous, V, Soares, D, Sarasin, A, Cook, P, Larsen, A
Format:	Journal article
Jezik:	English
Izdano:	2008

Slični predmeti

Enantioselective Total Synthesis of (−)-Acylfulvene and (−)- Irofulven
od: Movassaghi, Mohammad, i dr.
Izdano: (2012)

Enantioselective total syntheses of acylfulvene, irofulven, and the agelastatins
od: Siegel, Dustin S. (Dustin Scott), 1980-
Izdano: (2011)

Different populations of RNA polymerase II in living mammalian cells.
od: Hieda, M, i dr.
Izdano: (2005)

Different populations of RNA polymerase II in living mammalian cells
od: Cook, P, i dr.
Izdano: (2005)

Transcriptional mutagenesis induced by 8-oxoguanine in mammalian cells.
od: Damien Brégeon, i dr.
Izdano: (2009-07-01)

Coupled transcription and translation within nuclei of mammalian cells.
od: Iborra, F, i dr.
Izdano: (2001)

The transcription cycle of RNA polymerase II in living cells
od: Kimura, H, i dr.
Izdano: (2002)

The transcription cycle of RNA polymerase II in living cells.
od: Kimura, H, i dr.
Izdano: (2002)

Coordination of transcription-coupled repair and repair-independent release of lesion-stalled RNA polymerase II
od: Yongchang Zhu, i dr.
Izdano: (2024-08-01)

Molecular dissection of mammalian RNA polymerase II transcriptional termination.
od: West, S, i dr.
Izdano: (2008)

The transcription-repair coupling factor Mfd associates with RNA polymerase in the absence of exogenous damage
od: Han N. Ho, i dr.
Izdano: (2018-04-01)

Pause sites promote transcriptional termination of mammalian RNA polymerase II.
od: Gromak, N, i dr.
Izdano: (2006)

Mechanism of Rad26-assisted rescue of stalled RNA polymerase II in transcription-coupled repair
od: Chunli Yan, i dr.
Izdano: (2021-12-01)

The topology of transcription by immobilized polymerases.
od: Iborra, F, i dr.
Izdano: (1996)

Fixing the model for transcription: the DNA moves, not the polymerase.
od: Papantonis, A, i dr.
Izdano: (2011)

Monofunctional Platinum-DNA Adducts Are Strong Inhibitors of Transcription and Substrates for Nucleotide Excision Repair in Live Mammalian Cells
od: Zhu, Guangyu, i dr.
Izdano: (2012)

Design and use of Chikungunya virus replication templates utilizing mammalian and mosquito RNA polymerase I mediated transcription
od: Utt, A, i dr.
Izdano: (2019)

Transcription-Coupled Repair in Plants
od: Ana Lena Fidantsef, i dr.
Izdano: (2012-01-01)

Transcription by an immobilized RNA polymerase from bacteriophage T7 and the topology of transcription.
od: Cook, P, i dr.
Izdano: (1992)

Molecular cross-talk between the transcription, translation, and nonsense-mediated decay machineries.
od: Iborra, F, i dr.
Izdano: (2004)

Specialized transcription factories within mammalian nuclei.
od: Pombo, A, i dr.
Izdano: (2000)

Methylation of RNA polymerase II non-consensus Lysine residues marks early transcription in mammalian cells
od: João D Dias, i dr.
Izdano: (2015-12-01)

Yeast and mammalian RNA polymerase II holoenzymes
od: Chao, David M. (David Min)
Izdano: (2008)

Mammalian DNA Polymerase Kappa Activity and Specificity
od: Hannah R. Stern, i dr.
Izdano: (2019-08-01)

Does transcription by RNA polymerase play a direct role in the initiation of replication?
od: Hassan, A, i dr.
Izdano: (1994)

Comparison of Commercially Available Thermostable DNA Polymerases with Reverse Transcriptase Activity in Coupled Reverse Transcription Polymerase Chain Reaction Assays
od: Evgeniya V. Smirnova, i dr.
Izdano: (2025-01-01)

ACTIVE POLYMERASES FIXED IN REPLICATION AND TRANSCRIPTION FACTORIES
od: Hassan, B, i dr.
Izdano: (1994)

Mammalian cell lines expressing functional RNA polymerase II tagged with the green fluorescent protein.
od: Sugaya, K, i dr.
Izdano: (2000)

Measuring histone and polymerase dynamics in living cells.
od: Kimura, H, i dr.
Izdano: (2004)

Transcription Inhibition by Platinum DNA Cross-links in Live Mammalian Cells
od: Ang, Wee Han, i dr.
Izdano: (2011)

Time-resolved analysis of transcription kinetics in single live mammalian cells
od: Hongyoung Choi, i dr.
Izdano: (2022-11-01)

A-MYB and BRDT-dependent RNA Polymerase II pause release orchestrates transcriptional regulation in mammalian meiosis
od: Adriana K. Alexander, i dr.
Izdano: (2023-03-01)

Tyrosine phosphorylation of RNA polymerase II CTD is associated with antisense promoter transcription and active enhancers in mammalian cells
od: Nicolas Descostes, i dr.
Izdano: (2014-05-01)

Correction: Rad26, the Transcription-Coupled Repair Factor in Yeast, Is Required for Removal of Stalled RNA Polymerase-II following UV Irradiation
Izdano: (2013-01-01)

Correction: Rad26, the Transcription-Coupled Repair Factor in Yeast, Is Required for Removal of Stalled RNA Polymerase-II following UV Irradiation.
od: Sounak Ghosh-Roy, i dr.
Izdano: (2013-01-01)

DNA polymerase delta is required for early mammalian embryogenesis.
od: Arikuni Uchimura, i dr.
Izdano: (2009-01-01)

The proteomes of transcription factories containing RNA polymerases I, II or III.
od: Melnik, S, i dr.
Izdano: (2011)

Numbers and organization of RNA polymerases, nascent transcripts, and transcription units in HeLa nuclei.
od: Jackson, D, i dr.
Izdano: (1998)

Numbers and organization of RNA polymerases, nascent transcripts, and transcription units in HeLa nuclei
od: Jackson, D, i dr.
Izdano: (1998)

Biosurfactants as Potential Antitumor Agents
od: C. I., Ukaegbu, i dr.
Izdano: (2023)