Localization of a gene (MCUL1) for multiple cutaneous leiomyomata and uterine fibroids to chromosome 1q42.3-q43.

Dominant transmission of multiple uterine and cutaneous smooth-muscle tumors is seen in the disorder multiple leiomyomatosis (ML). We undertook a genomewide screen of 11 families segregating ML and found evidence for linkage to chromosome 1q42.3-q43 (maximum multipoint LOD score 5.40). Haplotype con...

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Bibliographic Details
Main Authors: Alam, N, Bevan, S, Churchman, M, Barclay, E, Barker, K, Jaeger, E, Nelson, H, Healy, E, Pembroke, A, Friedmann, P, Dalziel, K, Calonje, E, Anderson, J, August, P, Davies, MG, Felix, R, Munro, C, Murdoch, M, Rendall, J, Kennedy, S, Leigh, I, Kelsell, D, Tomlinson, I, Houlston, R
Format: Journal article
Language:English
Published: 2001