Long alkylchain iminosugars block the HCV p7 ion channel

The small p7 protein of the hepatitis C virus (HCV) and the closely related bovine viral diarrhea virus (BVDV) can form ion channels in artificial membranes Ion channel activity can be suppressed by long alkylchain iminosugar derivatives, which have been shown to be antiviral in BVDV infectivityass...

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Bibliografische gegevens
Hoofdauteurs: Pavlovic, D, Fischer, W, Hussey, M, Durantel, D, Durantel, S, Branza-Nichita, N, Woodhouse, S, Dwek, R, Zitzmann, N
Formaat: Journal article
Taal:English
Gepubliceerd in: Springer Verlag 2005