A positively charged channel within the Smc1/Smc3 hinge required for sister chromatid cohesion.

Cohesin's structural maintenance of chromosome 1 (Smc1) and Smc3 are rod-shaped proteins with 50-nm long intra-molecular coiled-coil arms with a heterodimerization domain at one end and an ABC-like nucleotide-binding domain (NBD) at the other. Heterodimerization creates V-shaped molecules with...

Full description

Bibliographic Details
Main Authors: Kurze, A, Michie, K, Dixon, SE, Mishra, A, Itoh, T, Khalid, S, Strmecki, L, Shirahige, K, Haering, C, Löwe, J, Nasmyth, K
Format: Journal article
Language:English
Published: 2011