Exhaustion of activated CD8 T cells predicts disease progression in primary HIV-1 infection

Exhaustion of activated CD8 T cells predicts disease progression in primary HIV-1 infection

<p>The rate at which HIV-1 infected individuals progress to AIDS is highly variable and impacted by T cell immunity. CD8 T cell inhibitory molecules are up-regulated in HIV-1 infection and associate with immune dysfunction. We evaluated participants (n=122) recruited to the SPARTAC randomised...

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Bibliografische gegevens
Hoofdauteurs: Hoffmann, M, Pantazis, N, Martin, G, Hickling, S, Hurst, J, Meyerowitz, J, Willberg, C, Robinson, N, Brown, H, Fisher, M, Kinloch, S, Babiker, A, Weber, J, Nwokolo, N, Fox, J, Fidler, S, Phillips, R, Frater, A
Formaat: Journal article
Gepubliceerd in: Public Library of Science 2016

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