SIDE-CHAIN SPECIFICITY IN THE ENZYMATIC-SYNTHESIS OF PENICILLINS

5-Carboxynaphth-1-oyl-, 4-carboxybenxoyl-,trans-5-carboxy-3-pentenoyl- and cis-5-carboxy-3-pentenoyl-L-cysteinyl-D-valine were shown to be converted by isopenicillin N synthetase to their corresponding penicillins in yields of 90%, 12%, 40% and 5%, respectively. © 1990.

Detalles Bibliográficos
Autores principales: Baldwin, J, Schofield, C, Smith, B
Formato: Journal article
Lenguaje:English
Publicado: 1990