The m74 gene product of murine cytomegalovirus (MCMV) is a functional homolog of human CMV gO and determines the entry pathway of MCMV.

The glycoprotein gO (UL74) of human cytomegalovirus (HCMV) forms a complex with gH/gL. Virus mutants with a deletion of gO show a defect in secondary envelopment with the consequence that virus spread is restricted to a cell-associated pathway. Here we report that the positional homolog of HCMV gO,...

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Bibliografski detalji
Glavni autori: Scrivano, L, Esterlechner, J, Mühlbach, H, Ettischer, N, Hagen, C, Grünewald, K, Mohr, C, Ruzsics, Z, Koszinowski, U, Adler, B
Format: Journal article
Jezik:English
Izdano: 2010