GTAC enables parallel genotyping of multiple genomic loci with chromatin accessibility profiling in single cells

Understanding clonal evolution and cancer development requires experimental approaches for characterizing the consequences of somatic mutations on gene regulation. However, no methods currently exist that efficiently link high-content chromatin accessibility with high-confidence genotyping in single...

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Bibliographic Details
Main Authors: Turkalj, S, Jakobsen, NA, Groom, A, Metzner, M, Riva, SG, Gür, ER, Usukhbayar, B, Salazar, MA, Hentges, LD, Mickute, G, Clark, K, Sopp, P, Davies, JOJ, Hughes, JR, Vyas, P
Format: Journal article
Language:English
Published: Cell Press 2023