Lighting up DNA with the environment-sensitive bright adenine analogue qAN4

The fluorescent adenine analogue qAN4 was recently shown to possess promising photophysical properties, including a high brightness as a monomer. Here we report the synthesis of the phosphoramidite of qAN4 and its successful incorporation into DNA oligonucleotides using standard solid-phase synthesi...

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Bibliographic Details
Main Authors: Füchtbauer, AF, Wranne, MS, Sarangamath, S, Bood, M, El-Sagheer, AH, Brown, B, Gradén, H, Grøtli, M, Wilhelmsson
Format: Journal article
Language:English
Published: Wiley 2020