Characterization of IgG autoantibodies to extracellular matrix protein 1 in lichen sclerosus.

Although the precise aetiology of lichen sclerosus is unknown, evidence for an autoimmune basis to the disorder is emerging. Indeed, circulating IgG autoantibodies to the glycoprotein extracellular matrix protein 1 (ECM1) have been demonstrated in the sera of about 75% of affected individuals. To as...

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Bibliographic Details
Main Authors: Chan, I, Oyama, N, Neill, S, Wojnarowska, F, Black, M, McGrath, J
Format: Journal article
Language:English
Published: 2004