Investigating the function of a pentameric ligand-gated ion channel with molecular simulation

<p>Pentameric ligand-gated ion channels (pLGICs) are key players in mediating fast neurotransmission. Upon neurotransmitter binding, they undergo conformational changes that lead to the opening of the channel pore, allowing ions to flow in or out of the cell. They are involved in a range of ne...

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Bibliographic Details
Main Author: Dämgen, MA
Other Authors: Biggin, P
Format: Thesis
Language:English
Published: 2019