Successful treatment without cranial radiotherapy of children receiving intensified chemotherapy for acute lymphoblastic leukaemia: results of the risk-stratified randomized central nervous system treatment trial MRC UKALL XI (ISRC TN 16757172).

Concern about late adverse effects of cranial radiotherapy (XRT) has led to alternative approaches to eliminate leukaemia from the central nervous system (CNS) in childhood acute lymphoblastic leukaemia (ALL). The Medical Research Council UKALL XI trial recruited 2090 children with ALL between 1990...

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Bibliographic Details
Main Authors: Hill, F, Richards, S, Gibson, B, Hann, I, Lilleyman, J, Kinsey, S, Mitchell, C, Harrison, C, Eden, O
Format: Journal article
Language:English
Published: 2004