Validation study of a quantitative multigene reverse transcriptase-polymerase chain reaction assay for assessment of recurrence risk in patients with stage II colon cancer.

PURPOSE: We developed quantitative gene expression assays to assess recurrence risk and benefits from chemotherapy in patients with stage II colon cancer. PATIENTS AND METHODS: We sought validation by using RNA extracted from fixed paraffin-embedded primary colon tumor blocks from 1,436 patients wi...

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Bibliographic Details
Main Authors: Gray, R, Quirke, P, Handley, K, Lopatin, M, Magill, L, Baehner, F, Beaumont, C, Clark-Langone, K, Yoshizawa, C, Lee, M, Watson, D, Shak, S, Kerr, D
Format: Journal article
Language:English
Published: 2011