Dicer dependent tRNA derived small RNAs promote nascent RNA silencing

In mammalian cells, small non-coding RNAs (sncRNAs) negatively regulate gene expression in a pathway known as RNA interference (RNAi). RNAi can be categorized into post-transcriptional gene silencing (PTGS), which involves the cleavage of target messenger RNA (mRNA) or inhibition of translation in t...

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Bibliographic Details
Main Authors: Di Fazio, A, Schlackow, M, Pong, SK, Alagia, A, Gullerova, M
Format: Journal article
Language:English
Published: Oxford University Press 2022