Simultaneous viral whole-genome sequencing and differential expression profiling in respiratory syncytial virus infection of infants

Targeted metagenomics using strand-specific libraries with target enrichment is a sensitive, generalized approach to pathogen sequencing and transcriptome profiling. Using this method, we recovered 13 (76%) complete human respiratory syncytial virus (RSV) genomes from 17 clinical respiratory samples...

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Bibliographic Details
Main Authors: Lin, G-L, Golubchik, T, Drysdale, S, O'Connor, D, Jefferies, K, Brown, A, de Cesare, M, Bonsall, D, Ansari, MA, Aerssens, J, Bont, L, Openshaw, P, Martinón-Torres, F, Bowden, R, Pollard, AJ
Other Authors: RESCEU Investigators
Format: Journal article
Language:English
Published: Oxford University Press 2020