Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse
<h4>Background</h4> <p>Mutations of the common cytokine receptor gamma chain (γc) cause Severe Combined Immunodeficiency characterized by absent T and NK cell development. Although stem cell therapy restores these lineages, residual immune defects are observed that may result from...
Main Authors: | , , , , , , , , , , |
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Format: | Journal article |
Published: |
Wellcome Trust
2017
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