Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse

Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse

<h4>Background</h4> <p>Mutations of the common cytokine receptor gamma chain (γc) cause Severe Combined Immunodeficiency characterized by absent T and NK cell development. Although stem cell therapy restores these lineages, residual immune defects are observed that may result from...

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Bibliographic Details
Main Authors: Beilin, C, Choudhuri, K, Bouma, G, Malinova, D, Llodra, J, Stokes, D, Shimaoka, M, Springer, T, Dustin, M, Thrasher, A, Burns, S
Format: Journal article
Published: Wellcome Trust 2017

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