Accelerating the clinical development of protein-based vaccines for malaria by efficient purification using a four amino acid C-terminal 'C-tag'.

Development of bespoke biomanufacturing processes remains a critical bottleneck for translational studies, in particular when modest quantities of a novel product are required for proof-of-concept Phase I/II clinical trials. In these instances the ability to develop a biomanufacturing process quickl...

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Bibliographic Details
Main Authors: Jin, J, Hjerrild, K, Silk, S, Brown, R, Labbé, G, Marshall, J, Wright, K, Bezemer, S, Clemmensen, S, Biswas, S, Li, Y, El-Turabi, A, Douglas, A, Hermans, P, Detmers, F, de Jongh, W, Higgins, M, Ashfield, R, Draper, S
Format: Journal article
Language:English
Published: Elsevier 2017