The effect of immune selection on the structure of the meningococcal opa protein repertoire.

The opa genes of the Gram negative bacterium Neisseria meningitidis encode Opacity-associated outer membrane proteins whose role is to promote adhesion to the human host tissue during colonisation and invasion. Each meningococcus contains 3-4 opa loci, each of which may be occupied by one of a large...

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Bibliographic Details
Main Authors: Callaghan, M, Buckee, C, Jolley, K, Kriz, P, Maiden, M, Gupta, S
Format: Journal article
Language:English
Published: Public Library of Science 2008