Vascular endothelial growth factor receptors VEGFR-2 and VEGFR-3 are localized primarily to the vasculature in human primary solid cancers.

PURPOSE: Vascular endothelial growth factor (VEGF) signaling is key to tumor angiogenesis and is an important target in the development of anticancer drugs. However, VEGF receptor (VEGFR) expression in human cancers, particularly the relative expression of VEGFR-2 and VEGFR-3 in tumor vasculature v...

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Bibliographic Details
Main Authors: Smith, N, Baker, D, James, N, Ratcliffe, K, Jenkins, M, Ashton, SE, Sproat, G, Swann, R, Gray, N, Ryan, A, Jürgensmeier, J, Womack, C
Format: Journal article
Language:English
Published: 2010