The hemopexin and O-glycosylated domains tune gelatinase B/MMP-9 bioavailability via inhibition and binding to cargo receptors.

Gelatinase B/matrix metalloproteinase-9 (MMP-9), a key regulator and effector of immunity, contains a C-terminal hemopexin domain preceded by a unique linker sequence of approximately 64 amino acid residues. This linker sequence is demonstrated to be an extensively O-glycosylated (OG) domain with a...

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Bibliographic Details
Main Authors:	Van den Steen, P, Van Aelst, I, Hvidberg, V, Piccard, H, Fiten, P, Jacobsen, C, Moestrup, S, Fry, S, Royle, L, Wormald, M, Wallis, R, Rudd, P, Dwek, R, Opdenakker, G
Format:	Journal article
Language:	English
Published:	2006

The hemopexin and O-glycosylated domains tune gelatinase B/MMP-9 bioavailability via inhibition and binding to cargo receptors.

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