Molecular fingerprinting reveals non-overlapping T cell oligoclonality between an inflamed site and peripheral blood.

We have demonstrated a stable expansion of CD8+ T cells in the peripheral blood of a child with chronic arthritis. The expanded TCRBV family (TCRBV14) was enriched for CD57hiCD28- T cells. Sequencing of the TCRBV14 amplification products showed a TCR sequence which contributed 32% of the total TCR i...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Wedderburn, L, Maini, M, Patel, A, Beverley, P, Woo, P
Format: Journal article
Język:English
Wydane: 1999