Structural characterization of mammalian bHLH-PAS transcription factors
The mammalian basic helix-loop-helix-PER-ARNT-SIM (bHLH–PAS) transcription factors share common architectural features that include a bHLH DNA-binding domain and tandemly positioned PAS domains. The sixteen members of this family include the hypoxia-inducible factors (HIF-1α and HIF-2α), ARNT (also...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2016
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