Molecular dynamics simulations of inwardly rectifying (Kir) potassium channels: a comparative study.
Inward rectifier potassium (Kir) channels regulate cell excitability and transport K+ ions across membranes. Homotetrameric models of three mammalian Kir channels (Kir1.1, Kir3.1, and Kir6.2) have been generated, using the KirBac3.1 transmembrane and rat Kir3.1 intracellular domain structures as tem...
المؤلفون الرئيسيون: | Haider, S, Khalid, S, Tucker, S, Ashcroft, F, Sansom, MS |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2007
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مواد مشابهة
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Conformational dynamics of the ligand-binding domain of inward rectifier K channels as revealed by molecular dynamics simulations: toward an understanding of Kir channel gating.
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