Molecular dynamics simulations of inwardly rectifying (Kir) potassium channels: a comparative study.

Inward rectifier potassium (Kir) channels regulate cell excitability and transport K+ ions across membranes. Homotetrameric models of three mammalian Kir channels (Kir1.1, Kir3.1, and Kir6.2) have been generated, using the KirBac3.1 transmembrane and rat Kir3.1 intracellular domain structures as tem...

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Autors principals: Haider, S, Khalid, S, Tucker, S, Ashcroft, F, Sansom, MS
Format: Journal article
Idioma:English
Publicat: 2007

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