Molecular dynamics simulations of inwardly rectifying (Kir) potassium channels: a comparative study.

Molecular dynamics simulations of inwardly rectifying (Kir) potassium channels: a comparative study.

Inward rectifier potassium (Kir) channels regulate cell excitability and transport K+ ions across membranes. Homotetrameric models of three mammalian Kir channels (Kir1.1, Kir3.1, and Kir6.2) have been generated, using the KirBac3.1 transmembrane and rat Kir3.1 intracellular domain structures as tem...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs:	Haider, S, Khalid, S, Tucker, S, Ashcroft, F, Sansom, MS
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	2007

Gelijkaardige items

Conformational dynamics of the ligand-binding domain of inward rectifier K channels as revealed by molecular dynamics simulations: toward an understanding of Kir channel gating.
door: Haider, S, et al.
Gepubliceerd in: (2005)

Mapping of the physical interaction between the intracellular domains of an inwardly rectifying potassium channel, Kir6.2.
door: Tucker, S, et al.
Gepubliceerd in: (1999)

Endocannabinoid regulation of inward rectifier potassium (Kir) channels
door: Sultan Mayar, et al.
Gepubliceerd in: (2024-08-01)

Phosphoinositide Regulation of Inward Rectifier Potassium (Kir) Channels
door: Oliver eFurst, et al.
Gepubliceerd in: (2014-01-01)

Multiple sites of interaction between the intracellular domains of an inwardly rectifying potassium channel, Kir6.2.
door: Jones, P, et al.
Gepubliceerd in: (2001)

Inwardly rectifying potassium channels.
door: Reimann, F, et al.
Gepubliceerd in: (1999)

Computer modelling and simulation studies of a human inwardly rectifying potassium channel Kir6.2
door: Capener, C, et al.
Gepubliceerd in: (2000)

Homology modeling and molecular dynamics simulation studies of an inward rectifier potassium channel.
door: Capener, C, et al.
Gepubliceerd in: (2000)

Defining how multiple lipid species interact with inward rectifier potassium (Kir2) channels
door: Duncan, AL, et al.
Gepubliceerd in: (2020)

Nuance of inward rectifying potassium (Kir) channel dysfunctions in neurodegenerative diseases
door: Benjamin Garland, et al.
Gepubliceerd in: (2024-01-01)

Role of Astrocytic Inwardly Rectifying Potassium (Kir) 4.1 Channels in Epileptogenesis
door: Masato Kinboshi, et al.
Gepubliceerd in: (2020-12-01)

Filter flexibility and distortion in a bacterial inward rectifier K+ channel: simulation studies of KirBac1.1.
door: Domene, C, et al.
Gepubliceerd in: (2004)

pH dependence of the inwardly rectifying potassium channel, Kir5.1, and localization in renal tubular epithelia.
door: Tucker, S, et al.
Gepubliceerd in: (2000)

Involvement of Inwardly Rectifying Potassium (Kir) Channels in the Toxicity of Flonicamid to <i>Drosophila melanogaster</i>
door: Xuan Liu, et al.
Gepubliceerd in: (2025-01-01)

Cloning, functional expression, and pharmacological characterization of inwardly rectifying potassium channels (Kir) from Apis mellifera
door: Fabien Sourisseau, et al.
Gepubliceerd in: (2024-04-01)

Diverse functions of the inward-rectifying potassium channel Kir5.1 and its relationship with human diseases
door: Chaojie Zhang, et al.
Gepubliceerd in: (2023-02-01)

Promiscuous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels.
door: Ammälä, C, et al.
Gepubliceerd in: (1996)

Discovery, characterization and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.X and Kir7.1
door: Jerod S Denton
Gepubliceerd in: (2011-11-01)

Pharmacological validation of an inward-rectifier potassium (Kir) channel as an insecticide target in the yellow fever mosquito Aedes aegypti.
door: Matthew F Rouhier, et al.
Gepubliceerd in: (2014-01-01)

INWARDLY RECTIFYING K+ CURRENTS IN OOCYTES CO-EXPRESSING KIR3.1 AND KIR3.2
door: Ammala, C, et al.
Gepubliceerd in: (1995)

Epsilon Toxin from <i>Clostridium perfringens</i> Causes Inhibition of Potassium inward Rectifier (Kir) Channels in Oligodendrocytes
door: Jean Louis Bossu, et al.
Gepubliceerd in: (2020-01-01)

Cloning and functional characterization of a superfamily of microbial inwardly rectifying potassium channels.
door: Sun, S, et al.
Gepubliceerd in: (2006)

Two types of gating in inward rectifiers: The case of the K-ATP channel.
door: Proks, P, et al.
Gepubliceerd in: (2001)

Inhibition of Inwardly Rectifying Potassium (Kir) 4.1 Channels Facilitates Brain-Derived Neurotrophic Factor (BDNF) Expression in Astrocytes
door: Masato Kinboshi, et al.
Gepubliceerd in: (2017-12-01)

Inward rectifier potassium (Kir) channels mediate salivary gland function and blood feeding in the lone star tick, Amblyomma americanum.
door: Zhilin Li, et al.
Gepubliceerd in: (2019-02-01)

Focus on Kir6.2: a key component of the ATP-sensitive potassium channel.
door: Haider, S, et al.
Gepubliceerd in: (2005)

Advancements in the study of inward rectifying potassium channels on vascular cells
door: Chunshu Li, et al.
Gepubliceerd in: (2023-12-01)

The sulphonylurea receptor confers diazoxide sensitivity on the inwardly rectifying K+ channel Kir6.1 expressed in human embryonic kidney cells.
door: Ammälä, C, et al.
Gepubliceerd in: (1996)

The inwardly rectifying K+ channel KIR7.1 controls uterine excitability throughout pregnancy.
door: McCloskey, C, et al.
Gepubliceerd in: (2014)

The inwardly rectifying K+ channel KIR7.1 controls uterine excitability throughout pregnancy
door: Conor McCloskey, et al.
Gepubliceerd in: (2014-07-01)

ATP-dependent interaction of the cytosolic domains of the inwardly rectifying K+ channel Kir6.2 revealed by fluorescence resonance energy transfer.
door: Tsuboi, T, et al.
Gepubliceerd in: (2004)

CHARACTERIZATION OF AN INWARDLY RECTIFYING K+ CHANNEL EXPRESSED IN PANCREATIC BETA-CELLS
door: Ashcroft, F
Gepubliceerd in: (1995)

Identification and distribution of inwardly rectifying potassium channels in rat microvascular endothelial cells
door: Hinton, J, et al.
Gepubliceerd in: (2000)

Identification and distribution of inwardly rectifying potassium channels in rat microvascular endothelial cells
door: Hinton, J, et al.
Gepubliceerd in: (2000)

Direct modulation of G protein-gated inwardly rectifying potassium (GIRK) channels
door: Ha Nguyen, et al.
Gepubliceerd in: (2024-06-01)

From in silico to in vitro: a trip to reveal flavonoid binding on the Rattus norvegicus Kir6.1 ATP-sensitive inward rectifier potassium channel
door: Alfonso Trezza, et al.
Gepubliceerd in: (2018-05-01)

Differential expression of the inwardly-rectifying K-channel ROMK1 in rat brain.
door: Kenna, S, et al.
Gepubliceerd in: (1994)

Characterization of the chicken inward rectifier K<sup>+ </sup>channel <it>IRK1/Kir2.1 </it>gene
door: Locke Emily, et al.
Gepubliceerd in: (2004-11-01)

H bonding at the helix-bundle crossing controls gating in Kir potassium channels.
door: Rapedius, M, et al.
Gepubliceerd in: (2007)

Inwardly rectifying potassium channels in rat hepatic artery endothelial and smooth muscle cells.
door: Walker, S, et al.
Gepubliceerd in: (2000)