The structure of an idarubicin-d(TGATCA) complex at high resolution.
The crystal structure of the DNA hexamer d(TGATCA) complexed with the anthracycline antibiotic idarubicin has been determined at 1.6 A resolution. The asymmetric unit consists of a single hexamer oligonucleotide strand, one drug molecule and 35 water molecules. The complex crystallizes in the tetrag...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1993
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