DMRT1 regulates human germline commitment

Germline commitment following primordial germ cell (PGC) specification during early human development establishes an epigenetic programme and competence for gametogenesis. Here we follow the progression of nascent PGC-like cells derived from human embryonic stem cells in vitro. We show that switchin...

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Bibliographic Details
Main Authors: Irie, N, Lee, S-M, Lorenzi, V, Xu, H, Chen, J, Inoue, M, Kobayashi, T, Sancho-Serra, C, Drousioti, E, Dietmann, S, Vento-Tormo, R, Song, C-X, Surani, MA
Format: Journal article
Language:English
Published: Springer Nature 2023