DMRT1 regulates human germline commitment
Germline commitment following primordial germ cell (PGC) specification during early human development establishes an epigenetic programme and competence for gametogenesis. Here we follow the progression of nascent PGC-like cells derived from human embryonic stem cells in vitro. We show that switchin...
Hauptverfasser: | Irie, N, Lee, S-M, Lorenzi, V, Xu, H, Chen, J, Inoue, M, Kobayashi, T, Sancho-Serra, C, Drousioti, E, Dietmann, S, Vento-Tormo, R, Song, C-X, Surani, MA |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
Springer Nature
2023
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