Direct evidence to support the fetal insulin hypothesis as the type 2 diabetes risk alleles at the CDKALI and HHEX-IDE gene loci reduce birth weight

Ижил төстэй зүйлс

• Type 2 diabetes risk alleles are associated with reduced size at birth.
  -н: Freathy, R, зэрэг
  Хэвлэсэн: (2009)
• Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function.
  -н: Pascoe, L, зэрэг
  Хэвлэсэн: (2007)
• Common variation in the FTO (fused toes) gene is strongly associated with adiposity measures in the northern finnish birth cohort of 1966
  -н: Bennett, A, зэрэг
  Хэвлэсэн: (2007)
• Type 2 diabetes transcription factor 7-like 2 (TCF7L2) risk alleles reduce beta-cell function and increase birth weight
  -н: Freathy, R, зэрэг
  Хэвлэсэн: (2007)
• Mutations in HHEX are not a common cause of monogenic forms of beta cell dysfunction.
  -н: Minton, J, зэрэг
  Хэвлэсэн: (2007)