Definitions and validation criteria for biomarkers and surrogate endpoints: development and testing of a quantitative hierarchical levels of evidence schema.

OBJECTIVE: There are clear advantages to using biomarkers and surrogate endpoints, but concerns about clinical and statistical validity and systematic methods to evaluate these aspects hinder their efficient application. Our objective was to review the literature on biomarkers and surrogates to dev...

Ամբողջական նկարագրություն

Մատենագիտական մանրամասներ
Հիմնական հեղինակներ:	Lassere, M, Johnson, K, Boers, M, Tugwell, P, Brooks, P, Simon, L, Strand, V, Conaghan, P, Ostergaard, M, Maksymowych, W, Landewe, R, Bresnihan, B, Tak, P, Wakefield, R, Mease, P, Bingham, C, Hughes, M, Altman, D, Buyse, M, Galbraith, S, Wells, G
Ձևաչափ:	Conference item
Հրապարակվել է:	2007

Definitions and validation criteria for biomarkers and surrogate endpoints: development and testing of a quantitative hierarchical levels of evidence schema.

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