Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation.

The gastrointestinal (GI) tract is the main interface where the body encounters exogenous antigens. It is crucial that the local response here is tightly regulated to avoid an immune reaction against dietary antigens and commensal flora while still mounting an efficient defense against pathogens. Fa...

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Bibliographic Details
Main Authors: Izcue, A, Coombes, J, Powrie, F
Format: Journal article
Language:English
Published: 2006