Maximum precision closed-form solution for localizing diffraction-limited spots in noisy images.

Super-resolution techniques like PALM and STORM require accurate localization of single fluorophores detected using a CCD. Popular localization algorithms inefficiently assume each photon registered by a pixel can only come from an area in the specimen corresponding to that pixel (not from neighbori...

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Autors principals: Larkin, J, Cook, P
Format: Journal article
Idioma:English
Publicat: 2012