Studies of the ATPase activity of the ABC protein SUR1.

The ATP-sensitive potassium (K(ATP)) channel couples glucose metabolism to insulin secretion in pancreatic beta-cells. It comprises regulatory sulfonylurea receptor 1 and pore-forming Kir6.2 subunits. Binding and/or hydrolysis of Mg-nucleotides at the nucleotide-binding domains of sulfonylurea recep...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: De Wet, H, Mikhailov, M, Fotinou, C, Dreger, M, Craig, T, Vénien-Bryan, C, Ashcroft, F
Format: Journal article
Sprache:English
Veröffentlicht: 2007