Dupuytren's disease: a localised and accessible human fibrotic disorder

We review the biology of Dupuytren's disease (DD), a common localised fibrotic disorder of the hand. The disease develops through a complex interplay of genetic and environmental factors, and epigenetic signalling. The early-stage disease nodules comprise a complex milieu of stromal and immune...

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Autori principali: Layton, TB, Williams, L, Nanchahal, J
Natura: Journal article
Lingua:English
Pubblicazione: Cell Press 2022