Chronic administration of a selective dopamine D-2 agonist: factors determining behavioral tolerance and sensitization.

The locomotor stimulant effects of sustained administration of a potent and selective dopamine (DA) D-2 receptor agonist, [+]-4-propyl-9-hydroxynaphthoxazine (PHNO), in rats were assessed 24 h a day during 12 h light-dark cycles. PHNO was administered continuously with subcutaneous implants of Alzet...

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Bibliographic Details
Main Authors: Martin-Iverson, M, Stahl, S, Iversen, S
Format: Journal article
Language:English
Published: 1988