Chronic administration of a selective dopamine D-2 agonist: factors determining behavioral tolerance and sensitization.
The locomotor stimulant effects of sustained administration of a potent and selective dopamine (DA) D-2 receptor agonist, [+]-4-propyl-9-hydroxynaphthoxazine (PHNO), in rats were assessed 24 h a day during 12 h light-dark cycles. PHNO was administered continuously with subcutaneous implants of Alzet...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
1988
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