Survival motor neuron protein regulates stem cell division, proliferation, and differentiation in Drosophila

Spinal muscular atrophy is a severe neurogenic disease that is caused by mutations in the human survival motor neuron 1 (SMN1) gene. SMN protein is required for the assembly of small nuclear ribonucleoproteins and a dramatic reduction of the protein leads to cell death. It is currently unknown how t...

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Bibliographic Details
Main Authors: Grice, SJ, Liu, J-L
Format: Journal article
Language:English
Published: Public Library of Science 2011