TRP-channels as key integrators of lipid pathways in nociceptive neurons.

TRP-channels are the most prominent family of ligand-gated ion channels for pain perception. In sensory neurons, TRPV1-V4, TRPA1 and TRPM8 are expressed and are responsible for the conversion of external stimuli to painful sensations. Under pathophysiological conditions, excessive activity of TRP-ch...

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Bibliografiske detaljer
Main Authors: Sisignano, M, Bennett, D, Geisslinger, G, Scholich, K
Format: Journal article
Sprog:English
Udgivet: 2014