Plasmodium falciparum: in vitro studies of the pharmacodynamic properties of drugs used for the treatment of severe malaria.

The speed and stage specificity of antimalarial drug action on the metabolic activities of cultured Plasmodium falciparum were studied for chloroquine (CQ), quinine (QN), artemisinin (AR), and sodium artelinate (SA). CQ had the most rapid onset of action on [3H]hypoxanthine and [3H]isoleucine uptake...

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Bibliographic Details
Main Authors: ter Kuile, F, White, N, Holloway, P, Pasvol, G, Krishna, S
Format: Journal article
Language:English
Published: 1993