The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.

The N-linked oligomannose glycans of HIV gp120 are a target for both microbicide and vaccine design. The extent of cross-clade conservation of HIV oligomannose glycans is therefore a critical consideration for the development of HIV prophylaxes. We measured the oligomannose content of virion-associa...

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Bibliografiske detaljer
Main Authors: Bonomelli, C, Doores, K, Dunlop, D, Thaney, V, Dwek, R, Burton, D, Crispin, M, Scanlan, C
Format: Journal article
Sprog:English
Udgivet: Public Library of Science 2011